PE-22-28

PE-22-28 Chemical Information:

• Chemical Name: Spadin-derived heptapeptide (Gly-Val-Ser-Trp-Gly-Leu-Arg)
• Molecular Formula: C₃₅H₅₅N₁₁O₉
• Molecular Weight: ~773.89 g/mol
• CAS Number: 1801959-12-5
• Compound Class: Synthetic peptide (spadin analogue, heptapeptide)

Product Description: PE-22-28 is a synthetic heptapeptide corresponding to residues 22–28 of spadin, a naturally occurring peptide fragment derived from the sortilin propeptide. The sequence represents a shortened analogue of the parent peptide. PE-22-28 is produced via solid-phase peptide synthesis (SPPS) and supplied as a lyophilized powder intended exclusively for controlled in-vitro laboratory research by qualified professionals. This product is not formulated for clinical, diagnostic, or therapeutic use. Research Applications:

• In-vitro investigation of TREK-1 (two-pore-domain potassium channel) modulation in cell-based assay systems
• Laboratory studies of sortilin-derived peptide structure–activity relationships
• Comparative evaluation of shortened spadin analogues for binding affinity and stability
• Analytical method development and reference characterization for sequence-specific peptides

Storage and Handling:

• Store lyophilized material at -20 °C for long-term stability
• Reconstituted solutions should be stored at 2–8 °C and used promptly
• Protect from light, heat, and repeated freeze–thaw cycles
• Handle using appropriate laboratory safety and aseptic techniques

Product Specifications:

• Purity: ≥99% (HPLC Certified)
• Appearance: White to off-white lyophilized powder
• Solubility: Soluble in suitable laboratory agents
• Form: Lyophilized powder

Compliance Notice: PE-22-28 is FOR RESEARCH USE ONLY. It is not intended for human or veterinary use. This product has not been evaluated by the FDA. Misuse of this product is strictly prohibited and may violate federal, state, or local laws. By purchasing this product, buyer represents and warrants that it will be used only for in vitro research purposes.

Product Usage: Not for Human or Veterinary Use

Pure Health Peptides products are supplied to qualified research professionals and institutional users for in vitro laboratory research only. KYC verification is required prior to order fulfillment, and we reserve the right to refuse orders that do not meet buyer qualification criteria. These products are not drugs, foods, cosmetics, diagnostic products, or dietary supplements, have not been evaluated by the FDA, and are not intended for human or animal use. Any such use is prohibited and may violate federal, state, or local law. By purchasing, the buyer represents and warrants that the product will be used solely for in vitro research. The buyer agrees to indemnify, defend, and hold harmless Pure Health Peptides, its officers, employees, and agents from and against any and all claims, damages, losses, liabilities, costs, and expenses (including reasonable attorneys fees) arising out of or relating to the buyer’s use, handling, storage, or disposition of the product in any manner inconsistent with its research-use-only designation or applicable law.